Aids
The AIDS-defining cancers are Kaposi sarcoma, certain lymphomas and cervical cancer.
What our notes say
- The AIDS-defining cancers are Kaposi sarcoma, certain lymphomas and cervical cancer. (Internal Medicine (MBIM 4100) main exam, Paper One: 3 July 2019)
- • Detailed sexual history since the possibility OF aids should be considered where there are unexplained respiratory symptoms or chest X-ray abnormalities evidence of opportunistic infections. (Examination of Respiratory system — Past Paper Questions & Answers)
- It is seen in immunocompromised patients, including those with HIV/AIDS. (Gastrointestinal and liver — Past Paper Questions & Answers)
- Charles, 34, with HIV/AIDS, has a painful rounded 1 cm penile ulcer with heaped-up edges and tender suppurative inguinal lymphadenopathy. (Treatment of Infectious Disease: 5-case clinical quiz)
- Cryptosporidium causes profuse watery diarrhoea and, in AIDS, biliary disease (AIDS cholangiopathy). (Internal Medicine CAT 1 (MBChB 4), 2022: liver, pancreas and bone marrow, 30 MCQ)
- Malaria (chronic, with splenomegaly), tropical splenomegaly syndrome, schistosomiasis, typhoid and brucellosis, tuberculosis, HIV and AIDS, lymphoma and leukaemia (chronic myeloid), histoplasmosis, and hepatosplenic causes such as chronic liver disease with portal hypertension. (Junior Clerkship in Internal Medicine (MBIM4100) main exam, Paper One: 31 Januar)
Study material on Aids
- EXAM NOTES: VIROLOGY YR3
- Mycoses: Superficial, Cutaneous & Systemic Fungal Infections
- VASCULAR PATHOLOGY — Must-Know Comprehensive Notes
- VASCULAR PATHOLOGY — Must-Know Notes
- VIROLOGY SEM 3 CRASHED
- Medical Microbiology III Exam: Viruses, Fungi & Diagnosis
- MEDICAL MYCOLOGY — LONG ANSWER QUESTIONS
- Cytomegalovirus (CMV) Guide: Pathogenesis, Dx & Treatment
- Master Medical Mycology: MKU Exam Guide for Fungal Diseases
- MYCOLOGY MCQs — Complete Bank
Practice questions on Aids
30-year-old male with AIDS, fever/night sweats/weight loss, cardiac mass, spindle cells with slit-like vascular spaces and surrounding RBCs. Most likely diagnosis?
- Atrial myxoma
- Angiosarcoma
- Rhabdomyoma
- Cardiac fibroma
- Kaposi sarcoma
Answer: E. - HHV-8-associated **Kaposi sarcoma** in an AIDS patient; classic histology is spindle cells forming **slit-like vascular spaces** with extravasated RBCs ---
Which is NOT a class of drugs used in HIV/AIDS therapy?
- Synthetic nucleotides
- Reverse transcriptase inhibitors
- Ribozyme inhibitors
- Protease inhibitors
Answer: C. Ribozyme inhibitors are NOT an established class of HIV drugs. The recognized classes of antiretrovirals include NRTIs, NNRTIs, protease inhibitors, integrase inhibitors, fusion inhibitors, and CCR5 antagonists. ---
A 30-year-old male with AIDS presents with fever, night sweats, and weight loss. A cardiac mass is found on echocardiography. Biopsy reveals spindle cells with slit-like vascular spaces and surrounding red blood cells. What is the MOST likely diagnosis?
- Rhabdomyoma
- Cardiac myxoma
- Atrial myxoma
- Kaposi sarcoma
- Angiosarcoma ✅ Answer: D
Answer: A. The histological description (spindle cells, slit-like vascular spaces, red blood cells) is characteristic of Kaposi sarcoma, a common malignancy in AIDS patients.
Which statement regarding epidemiology of candidiasis is correct? Oral thrush is extremely common in AIDS/immunosuppressed patients. ---
- Bone marrow transplant patients are not at risk for systemic candidiasis
- Patients with low neutrophils/monocytes are not at risk
- Diabetics have enhanced resistance to candidiasis
- AIDS patients frequently develop mucocutaneous candidiasis, such as thrush
- Pregnancy lowers risk of candidal vaginitis
Answer: D.