Cellular Injury
Enzymes are also classified by their location within the cell, which dictates their release mechanism during cellular injury:
What our notes say
- Enzymes are also classified by their location within the cell, which dictates their release mechanism during cellular injury: (Clinical Enzymology and Biomarkers)
Study material on Cellular Injury
Practice questions on Cellular Injury
A 45-year-old man has a traumatic injury to his forearm and incurs extensive blood loss. On physical examination in the emergency department his blood pressure is 70/30 mm Hg. Which of the following cellular changes is most likely to represent irreversible cellular injury as a result of this injury?
- Epithelial dysplasia
- Cytoplasmic fatty metamorphosis
- Nuclear pyknosis
- Atrophy
- Anaerobic glycolysis F. Autophagocytosis
Answer: C. The hypotension leads to diminished tissue perfusion with ischemic injury. Nuclear chromatin clumping is reversible, but nuclear pyknosis is not. ---