Chronic Liver Disease
Also written as CLD.
Persons with chronic carrier states are predisposed to chronic liver disease and have a more than 200-fold increased risk of hepatocellular carcinoma
What our notes say
- Persons with chronic carrier states are predisposed to chronic liver disease and have a more than 200-fold increased risk of hepatocellular carcinoma (Paediatrics end of second semester exam (MBPE 4300): 4 October 2022, cardiology,)
- Physical examination shows a soft abdomen with mild tenderness over the liver edge; no scleral icterus or stigmata of chronic liver disease are evident. (Hepatitis B and the approach to hepatitis)
- | Past liver disease | *Known cirrhosis, hepatitis B/C, alcoholic liver disease, schistosomiasis, sickle‑cell hepatopathy?* | Underlying chronic liver disease sets the stage; tropical causes (schistosomiasis, sickle‑cell) are common in Kenya. | (Hepatic encephalopathy)
- Hepatorenal syndrome (HRS) is a functional, rapidly progressive renal failure that occurs in patients with advanced chronic liver disease (usually cirrhosis) or acute severe liver injury, in the absence of intrinsic kidney pathology. (Hepatorenal syndrome)
- The stigmata of chronic liver disease in childhood include all of the following EXCEPT: (Paediatrics end of 2nd semester exam (MBPE 4300): 5 October 2021, 50 MCQs)
- Chronic liver disease causes loss of body hair rather than hirsutism. (Paediatrics end of 2nd semester exam (MBPE 4300): 5 October 2021, 50 MCQs)
Study material on Chronic Liver Disease
- Chronic liver disease and cirrhosis
- Liver Histology & Physiology
- Liver Histology & Physiology
- Hepatorenal syndrome
- High-Yield Clinical Exam Notes: Cranial Nerves, Respiratory, Cardio
- Junior Clerkship in Internal Medicine (MBIM4100) main exam, Paper One: 31 January 2024
- Hepatic encephalopathy
- Chemical Pathology Practice Examination
- Liver Histology, Physiology and Pathology — Practice Questions
- Liver Histology, Physiology and Pathology — Practice Questions
- Liver Histology, Physiology and Pathology — Practice Questions
- Liver Histology, Physiology and Pathology — Practice Questions
- Liver Histology, Physiology and Pathology — Practice Questions
- Liver Histology, Physiology and Pathology — Practice Questions
Images

Practice questions on Chronic Liver Disease
A 58-year-old female presents with multiple bilateral liver lesions. She has no history of chronic liver disease. What is the most common diagnosis for malignant liver tumors in adults?
- Primary Hepatocellular Carcinoma
- Metastatic Carcinoma
- Primary Cholangiocarcinoma
- Angiosarcoma
Answer: B. Metastatic disease (especially from colon, lung, or breast) is far more common than primary liver cancer in non-cirrhotic livers.
A 58-year-old female presents with multiple bilateral liver lesions identified on CT scan. She has no known history of chronic liver disease or primary liver tumors. What is the most common diagnosis for malignant liver tumors in adults?
- Hepatocellular Carcinoma
- Cholangiocarcinoma
- Metastatic Carcinoma
- Liver Cell Adenoma
Answer: C. Metastatic carcinoma (secondary liver cancer) is the most common hepatic malignancy overall, far outnumbering primary liver tumors.