Signal Transduction
All the following are categories of receptors based on their associated mechanisms of signal transduction, EXCEPT:
What our notes say
- All the following are categories of receptors based on their associated mechanisms of signal transduction, EXCEPT: (cat 2 2014 — Source Paper Awaiting Edit)
- All the following are categories of receptors based on associated signal transduction mechanisms, EXCEPT: *(repeat of Paper 1 Q6 — Answer: d, heterotrimeric GTP receptors)* (cat 2 2014 — Source Paper Awaiting Edit)
- The most commonly mutated oncoprotein in all tumors and a key participant in abnormal signal transduction pathways is (Pathology Continuous Assessment July 2021)
- The most commonly mutated oncoprotein in all tumors and a key participant in abnormal signal transduction pathways is: (Medical MCQs: Chemical Pathology & Haematology Exam Review)
- Signal transduction is the intricate series of events and molecular components involved in transmitting a signal from the exterior to the interior of a cell. (LECTURE 2B: Signal Transduction and Second Messengers)
- Signal Initiators: These are the molecules that trigger the signal transduction pathway, such as hormones or other ligands. (LECTURE 2B: Signal Transduction and Second Messengers)
Study material on Signal Transduction
- LECTURE 2B: Signal Transduction and Second Messengers
- Physio Y1 EOY 2021
- Endocrine and Metabolic Pathology MCQs
- Mechanisms of Hormone Action
- Signal Transduction and Second Messengers
Practice questions on Signal Transduction
What is the relationship between TGF-β receptors I and II in signal transduction?
- They function independently
- They form a complex upon ligand binding
- Only receptor I is active
- They antagonize each other
- Primarily an incidental laboratory finding
Answer: B. TGF-β regulates cellular processes by binding to a complex composed of TGF-β receptors I and II. Dimerization of the receptors upon ligand binding initiates the signaling cascade. ---
All the following are categories of receptors on the basis of their associated mechanisms of signal transduction, EXCEPT ---
- G protein-coupled receptors
- Catalytic receptors
- Nuclear receptors
- heterotrimeric guanosine triphosphate (GTP) receptors
- ligand-gated ion channels
Answer: A.
The most commonly mutated oncoprotein in all tumors and a key participant in abnormal signal transduction pathways is ---
- APC
- TP53
- BRAF
- RAS
Answer: D.